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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c75e435754bf9e06cbfc85487db79fdc5e500e88f1f4340c464963148c875bd1' 
  AND token = 'IhXsd8siFpf2sGViVKGN8lW9X5zBT6Hf2ejwim9YWbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}