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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2885a45282c52ff99c19785ef37dbf62360c873163115f308be87b0147069018' 
  AND token = 'EcJp1Nd8hjrO1SJToXmf1FsILHR8g9Mq3PfUzQh3oKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}