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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '646ee0d9d7612b648b9869e5f50a6da72a4bb5979670ecc7f95ab9dd43dcd72f' 
  AND token = 'oZ4D4HdtEwtsdHleFYrMFW7Elz3GUFzjWYyOzsBkcq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}