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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d1282f8aa4aada1d48ec766ba71e5c5a02b6756d59fb3dab4a7141ba00f4da' 
  AND token = '8xPAaN9g1+ggw46a4MXCRbx0yiNzgekZ2mpj1ttquv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}