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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3dade8778c2aca3527e6b13e94455d1b7d1765363a04cbfd07fa07d754b9669' 
  AND token = 'q5rsUQk9WFix8jvT9D9U0KUmh2k/mHlDpfHYyxv/KtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}