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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '529abd01454a060b837a61e55e72f8cb666dc57928788d27594b36a1908fc416' 
  AND token = 'sKQ2AVGft2tHfI4XD3QXCGWAMkJCJik+qrJ1mNu/CK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}