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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df9df3d488d0a47110ee2f10b71614c92f9678954729ce76f7ee84ecc421366' 
  AND token = 'G2VVnDuM2wHHfw501wRXAwaDE5jvXj0vOSQyqcMIyBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}