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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae4fe30469a516fb389a170f43f40e556c4dbbbd792f0137e9957a1e6c3dc11' 
  AND token = 'ZNHxBcTY2EyJDby6TWKMf2LHquMUWj3EKUx0lcQeJkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}