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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7e0f69c99c96e2e262a95924c3abab7d9d1a7d0ae9f433fbffcf0aa13277372' 
  AND token = 'Qco6WVixnYQ+zg+t2qKXvF9M2/QcYTPv6UveOV1m8oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}