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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ff66020eb5738a5cdf6b453a9e46ea257c9f882339920285cd0b69bc41cbdf0' 
  AND token = '6md7hJLD4VE9do3pGeoBdPiXo3zZzkt2vUcfNH7kQO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}