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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cbd6ed63429d9f421d375437837dd7024ee8dd884d4215614c85359c68e8256' 
  AND token = 'ATkSeGXPJez03MF2bt3h7+vnFfAGXm8w3XcULGyPh2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}