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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '371926c29b04fa88d5b54d951232dfad7bc6c6a9c6d8ea2721c9fe707031e8e6' 
  AND token = 'CXiRt6QL04RSB4j+09FvtpSPnMBUP6JyZf0MNUSRAgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}