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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f683746813caa039397d262a1b5fd164667395f89a296a0909651e7ea3c409' 
  AND token = 'n+X0z6q7MNo63FaV8qWBR82XO0tvNL2eVQEze5uU7JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}