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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a741f0d13d557f01bb77fed16de4593c8b9aa44bcb4f037313a484fc7355adde' 
  AND token = 'RjRwIons5XzKKmzT0nsmWzIIwsIT/+YmgAcwDgG8Tz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}