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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7be4165f6904a895513260445f455a6ef5cf18ebbafed596b58daa6b8aa6923b' 
  AND token = 'ydLNdAgGw6Js+9kQk6YPmGZNJSgAtz8N8Z5ITGYmSXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}