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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461ba67ed4a2089409c66f56131280c22847db60d2eafd224a859853ebb39696' 
  AND token = '+GRO+MB3qtRvQPtr70257YD247H5LXil4JoEziyqBQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}