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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e316ee6ce0112c7f4a94397459f971d0d5fa576038a4150f638937d7f5e8578' 
  AND token = 'gpYunmbNKO5SiPhXiSpBUAnOKTWcAMQFEaw6kMuzw1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}