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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d9959994a922dd61957e45801739107da81b1285ceee770c4b47f948fc802ec' 
  AND token = 'CV6jxpJlBGQu+7/MdoZHW0LlFBx423eANIOwVldysV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}