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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef8a5b3cc644acacf1327977a223365712b4d8ce8ed948a37e2c230597b9d940' 
  AND token = '2SxD6BQ6AszTPjGsfF7qxN8e53WQ9KEhmldZghyqDtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}