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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f5bdb2aa914a27d4590f52b18e7df6c5fac9bd762ddd4ea50233746cc37ec6' 
  AND token = '7+g1Tmyt/qMPwmtRRixzMEDDSmvKz9UYjGD6ebWr6EQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}