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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0371105e5ba55a9e689ce0031f5401d4d9dedf6466a6c1e7915cf1a96a80925' 
  AND token = 'U5ICsi4tEpwIE8hHh/cd+mVdZr92xTyJ2PoQ61Pm54c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}