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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c8dda5e6edbe15aae0fc0c971a981e0c0597dcab5b2e9a51c726bd734e45543' 
  AND token = 'jBFIvmffM0a7qYyF3bafGcpLqMlv4FZ4LhA03gibfXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}