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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71e9bfe59a78f0c9c2f760df7b7a89e22dc9f50fb115a4babd8310651f21bd1d' 
  AND token = '726I9lA+MDw+Wmj2Ll4TVq6j+ynqdT/NpfJzF7HSh0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}