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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c39d1488aea55913a12d087dff1909cad8fbce484cf3645b371293b3d80a37f6' 
  AND token = 'OTGXdk2xXoo7KT1wKT6JUcFs/K4Xf00jkbdsXUo05vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}