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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74642d1f982b6c0726232db82a3810e903bb7ce87d63972c87875d0ae19f4ada' 
  AND token = 'RTpzMzNhpUH2d2VE9+Y0DyQSVeVhwiud7+Sm50xJJRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}