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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8f2ae2aac75f36e779cacb8549393e8fcde5c34efa4a9380f6f4de9b65115b' 
  AND token = '5wi5aijTeyqFPj+P0y2KW2n0pb+QI1SKZvgJ82x/T1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}