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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00479aa5fcd9b6f3c037fa9c83eddee6ba79ac245740f7a4e278b214f5015d01' 
  AND token = 'G0X4V8jtNyxLQxi/YNzpIYpzF3yFo0Sc0HLzhGd2SxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}