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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9074f53a45f50ebc90a7b40da4b71dd3802e8d804dad4bb296d7f707d014f219' 
  AND token = 'QmH+NYS080+xzT4QeaEfom0imRsti2xcNhawS/9XYqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}