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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a7b80c48579b1b1ed62dbe073a4a4849b7bf2ee8ecf0a2c84692fcb95ba4fb' 
  AND token = 'ebE5RkWoAeDJkyuxosq+HVNWApEbK+c20xJXYOclW6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}