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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743059cfce066045c8e614a5e1706e37275eb7688c4d173a7a2287de245e68d6' 
  AND token = 'fItXIE/oG9j/NR1JRfi4ChNFp0keo5RDVaccAL8cnKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}