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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b29786f133bf904c7628bacc2d7c34e73920c45d1ab9746b8b19c6e6ef216d05' 
  AND token = 'mAcLIUxd82P4Hhd9E6xuN748SBFPE71LUDTEiCnZdCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}