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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c749faa0ebfbca15fbcfa8de8b209180d059872c963c458fffaf6e016d1e7421' 
  AND token = '6vrzjcxJIo25CusvQL9+E0YYrrh6kCaRREVn4a5yXrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}