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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20122f0062155257aefc0d4a8ab6e374a0a952f99a07ffb9fcbd81fbd1fc9ffa' 
  AND token = 'dTOkfIitnSMlpUADPdGabkahG7RTr9V1SDQe64lcPdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}