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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57c08358ce08daa232ce7613139c9ff9417bc00e56b92e109fa733f4cebf13f2' 
  AND token = 'uIXJqEychpvd+M1BKo/HWh98vOpnO14t6M8W7hKF7hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}