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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '057dc6edc8b81e0138b36bb628625722189d50d3cd3638fc8bef61529116c298' 
  AND token = 'A7FyqY3RmM3j5Mc4rE/50D/2RXGXnd6RaLw1Gz72Z6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}