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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4063d13b12155025a92303424a5bc738caf2f2a82a4c06880a9149af39dcfd4c' 
  AND token = 'w1xQkLHcUb0fE+XnesqQU72P3WQLVF3pjS+iPUACC2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}