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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4972b002d2e318f4534b78d11a91e8035a733db043a9a12bf991a23dda294f56' 
  AND token = 'BQA++xHTH63t8uK5E7+YNaM9rENyIrdDTSr7f78SX9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}