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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef5f7333fd31f1fd60a81c15b2211aa57d1c12ead11d29129d8034965fa2a82' 
  AND token = 'v3Yg2NxDAcVRoONDzbiljCxAXvn5YkxyD9NLfPiaXvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}