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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72d7e741b80a774aed696cae06694f63fe52c7d51801b0d378def8ec24929aa' 
  AND token = 'MUPEyu5DyLt4ITY+9Dk8uQWAIdYN9xYtyk3doLGiNBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}