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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8872394dca889b3b5193a76047c6b597b01c195c6e0a36f1ae3a8a8d69c6648b' 
  AND token = 'bwvNxwGvcKWMagMcBN5+fVlgwgj8BVbQiW4zoRVAaeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}