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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543190611e438a43e2d99d5501dcecdf0f4a63e7e0ce0f36c70aaf4add1152dc' 
  AND token = 'y0tYbEqdFm4q1yzv5j+ykN8dz8zJjlALF+ed2npGji0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}