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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16bb2ef6a6fc58a0aacd5f463aa68dac80e8381727a1924625fb3671679c7697' 
  AND token = '8qsSI0vlKcNgfrB5F6+RUoQJiuupd6NiepDRAU/nQQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}