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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88a0b53b9c899b6525a9b9fe34393343441affd1c60bb8ed5a6fce5ed383d304' 
  AND token = 'crXJblIVvG3fBPRPfFAiEQIJrMxHvhwBa1cBCXrIBHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}