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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e565e37ee5d262def5c1c10bcb6391a564e9c39e365ad2680a1f48536b07dca' 
  AND token = 'XY5O0YVc1qLosjUrctBwB1FTOsR51fXhxqlN/TNZcaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}