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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4262b49e2d69d35a52bd42b5dcc4a173d047282c1e9af7040816a80cf6c53d08' 
  AND token = 'VUWv0lwtIezuQLk5ffZb+YkTz1OopZETg6eIXvtQgHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}