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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27cf3478398984b9a36f0e1bc4ffd1e7ac05167ca3870c169dc139e2978da232' 
  AND token = 'B4H/4TOe1w99CJIKsFVzuFZxHUBsejQfDc24W07k3pY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}