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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad7592e229d61140e7d34510b9f576e1d2bb384e80c7f4c0028e873a87c55434' 
  AND token = 'OcjeZStHrcqheT7P8b1xCWp+VfItWbCZvQTQ8wL6DuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}