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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25252967a27366ca40f6659bf35e53d108921188d2868f283c53fcca60fea4f2' 
  AND token = 'JZ8jsASDA0Wm/bi5nekYFu5oNAxNrsij2OOMCUZOlsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}