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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '236160aaaaeacf3347decfc07a893b23adfac05005f259ff86b9d350020e6535' 
  AND token = '443S1EPdDwNQQEL+VXzh42g9fTBqSkam7I9GemPp318=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}