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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3348901f2ca45f992e93835c1074e42413e19e370e11cd882d3b7e5f6f3002c9' 
  AND token = 'UG3o2Svv27SZC6d/cSRLCg3mj8RM2w3YW8n7C3kG+uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}